Interdisciplinary Oncology Program

Faculty of Medicine

100-570 West 7th Avenue
Vancouver, British Columbia V5Z 4S6

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Dr. David Kitts

My research discipline is Food Chemistry and Toxicology. I employ many aspects of food chemistry principles to understand the cellular and molecular mechanisms of both nutrient and food toxicant action in living organisms. Recently, my laboratory has focused on characterizing the mechanisms of antioxidant and prooxidant activity for many naturally occurring animal and plant constituents, in addition to derived products from food processing. Moreover, we have focused also on the interaction between food constituents and transition metals in modulating generation of free radical and peroxidation reactions that can alter stability of lipids in both food materials as well as biological membranes.

Lab website: http://www.landfood.ubc.ca/person/david-kitts/

Email: david.kitts@ubc.ca

Dr. Nathan Lack

Dr. Nathan Lack is a Senior Research Scientist at the Vancouver Prostate Centre.

 

He obtained a DPhil (PhD) in Pharmacology from the University of Oxford in 2009 and then did a Postdoctoral Fellowship at the Vancouver Prostate Centre with Dr. Emma Guns and Professor Paul Rennie. Nathan became an Assistant Professor at Koç University in the School of Medicine (Istanbul) in 2011 and was awarded Associate Professorship in 2015. In addition to his academic research, Nathan previously worked for AnorMED Inc., where he was involved in the development of the FDA-approved therapeutic Plerixafor.

 

His laboratory works to better understand the molecular underpinnings of prostate cancer to develop more effectively treatments for this common disease. Extensive clinical and basic research has shown that Androgen Receptor (AR)-mediated transcription drives the proliferation and growth of almost all prostate cancers. His group currently studies a diverse group of problems related to AR signaling including:

 

  • Identification of small molecule AR inhibitors that target novel sites

  • Characterization of non-coding mutations that affect androgen receptor signalling

  • Development of novel functional genomic techniques to study AR-mediated transcription

 

Since it’s initiation, the Lack laboratory has obtained extensive funding from national, international and industrial sources.

Lab Website: http://www.prostatecentre.com/about-us/people/dr-nathan-lack

Email: nlack@prostatecentre.com

Dr. Stephen Lam

Stephen Lam MD, FRCPC is Professor of Medicine at the University of British Columbia and a Distinguished Scientist, the Leon Judah Blackmore Chair in lung cancer research and MDS-Rix endowed director of translation lung cancer research at the BC Cancer Research Center. He chairs the BC Cancer Agency Provincial Lung Tumor Group. His research interest is in screening, chemoprevention and endoscopic diagnosis of early lung cancer. He has published over 280 peer reviewed papers and book chapters. He was the recipient of the IASLC Joseph Cullen Award for life-time scientific achievements in lung cancer prevention research, the Friesen Rygiel Award for Outstanding Canadian Academic Discovery, the Gustav Killian Medal by the World Association of Bronchology for pioneering contributions to the field early lung cancer diagnosis, as well as the Killam Research Prize in Applied Sciences and the Distinguished Achievement Award from the University of British Columbia. Dr. Lam received his medical training at the University of Toronto. He joined the UBC Faculty of Medicine in 1979 and the BC Cancer Agency in 1984.

Lab website: http://medicine.med.ubc.ca/stephen-lam/

Email: slam@bccancer.bc.ca 

Dr. Kelly McNagny

Kelly McNagny, PhD, is Professor of Medical Genetics, Co-Director of the Biomedical Research Centre, and Co-Scientific Director of the Centre for Drug Research and Development at UBC. He holds leadership positions in the Stem Cell NCE (Sub-Chair of the Training and Education Committee) and the AllerGen NCE (Associate Director of the Network and Program leader for the Biomarkers and Bioinformatics Program).  He is an expert in animal models acute and chronic mucosal inflammatory disease, innate immune response, stem cells, fibrotic disease and cancer.

Lab website: http://brc.ubc.ca/research/hematopoietic-cell-development-k-mcnagny/

Email:  kelly@brc.ubc.ca

Dr. Gregg Morin

The general theme of our research program is to understand the functional mechanisms of somatically mutated or differentially expressed proteins in cancer pathology. The research integrates proteomic, genomic, chemical biology and bioinformatic technologies with more traditional biochemical and molecular biology methodologies. Our goal is to develop large scale integrative programs to understand the causes, and identify therapeutic targets, for multi-factorial diseases such as cancer. To learn more about Dr. Morin's research, read The Protein Link to Cancer, published in the BC Cancer Foundation Spring 2015 Partners in Discovery magazine.

The functions of most proteins are defined by or mediated through interactions with other proteins. These interactions are organized into complex networks regulated, in part, through modulation of protein phosphorylation by an elaborate interconnected system of kinases and phosphatases. We use quantitative proteomic techniques to study how protein networks, protein-protein interactions and post-translational modifications are aberrantly regulated in cance

Lab website: http://www.bcgsc.ca/faculty/gmorin

Email: gmorin@bcgsc.ca

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